Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Merck Sharp & Dohme LLC

Urinary Bladder Neoplasms

NCT04700124
recruiting

Enrollment Count
784
ESTIMATED

Enrollment Rate
High

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

Merck Sharp & Dohme LLC

Urinary Bladder Neoplasms

NCT03924856
active not recruiting

Enrollment Count
907
ACTUAL

Enrollment Rate
High

Treating Muscle-invasive Bladder Cancer With A Non-surgical Method Consisting of Anti-PD-1 Therapy and Chemoradiation

Sun Yat-sen University

Urinary Bladder Neoplasms

NCT05975307
not yet recruiting

Enrollment Count
64
ESTIMATED

Enrollment Rate
Low

A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

Memorial Sloan Kettering Cancer Center

Urinary Bladder Neoplasms

NCT03520491
recruiting

Enrollment Count
45
ESTIMATED

Enrollment Rate
Low

Hypofractionated IMRT With Concurrent Chemotherapy in Muscle-invasive Bladder Cancer (HIRACUM)

Samsung Medical Center

Urinary Bladder Neoplasms

NCT05453682
recruiting

Enrollment Count
53
ESTIMATED

Enrollment Rate
Low

a Genome-based Platform to Predict Patients That Can Achieve Bladder Preservation in Muscle Invasive Bladder Cancer Patients

Yonsei University

Urinary Bladder Neoplasms

NCT04686149
not yet recruiting

Enrollment Count
39
ESTIMATED

Enrollment Rate
High

Effect and Prognosis of Immunohistochemical Biomarkers Changes in Patients With Bladder Cancer After Neoadjuvant Chemotherapy

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Urinary Bladder Neoplasms

NCT04966975
not yet recruiting

Enrollment Count
60
ESTIMATED

Enrollment Rate
Medium

Multicentric Prospective T1 Urinary Bladder Cancer Registry

Medical University of Vienna

Urinary Bladder Neoplasms

NCT05792033
recruiting

Enrollment Count
700
ESTIMATED

Enrollment Rate
High

Neoadjuvant Chemotherapy in Non Muscle Invasive T1b Bladder Cancer

Assiut University

Urinary Bladder Neoplasms

NCT04245618
not yet recruiting

Enrollment Count
50
ESTIMATED

Enrollment Rate
High

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

Merck Sharp & Dohme LLC

Urinary Bladder Neoplasms

NCT03924895
recruiting

Enrollment Count
857
ESTIMATED

Enrollment Rate
High

A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer

Pfizer

Urinary Bladder Neoplasms

NCT04165317
active not recruiting

Enrollment Count
1070
ACTUAL

Enrollment Rate
High